JCVI: Clustering of Highly Homologous Sequences to Reduce the Size of Large Protein Databases.
 
 
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Citation

Li W, Jaroszewski L, Godzik A

Clustering of Highly Homologous Sequences to Reduce the Size of Large Protein Databases.

Bioinformatics (Oxford, England). 2001 Mar 01; 17: 282-3.

External Citation

Abstract

We present a fast and flexible program for clustering large protein databases at different sequence identity levels. It takes less than 2 h for the all-against-all sequence comparison and clustering of the non-redundant protein database of over 560,000 sequences on a high-end PC. The output database, including only the representative sequences, can be used for more efficient and sensitive database searches.

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