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About the Center
The J. Craig Venter Institute (JCVI, formerly The Institute for Genomic Research) has been awarded a contract from the National Institute of Allergy and Infectious Diseases to establish the Pathogen Functional Genomics Resource Center (PFGRC). The PFGRC provides scientists with centralized resources necessary to conduct functional genomics studies on a variety of pathogens for which genomic sequence information is currently, or will soon be, available. The Center supports five programs: DNA microarrays, the Invitrogen Gateway® Entry Clone Resource, Comparative Genomics, Proteomics, and Bioinformatics support. The near-term goals of the PFGRC are to provide microarray, genotyping, proteomics, clone access, bioinformatics, and repository support surrounded by a Center-Client web-based interface allowing access to resource acquisition, data, and data analysis.
Recent News
January 19, 2011 The PFGRC posts revised table with updated GEO accessions for DNA Microarray Platforms
The PFGRC has revised the table available at GEO Accession Numbers which provides the GEO accession numbers for all PFGRC DNA microarray oligos and printing designs. The spreadsheet has been updated with Accession Numbers referencing… more
December 22, 2010 The PFGRC announces the availability of microarray and proteomics data management and analysis software through SourceForge
In cooperation with the Pathogen Portal and SourceForge, the PFGRC has made program source files, executables, and documentation for the following bioinformatics data management and analysis tools available for download through the SourceForge… more
November 5, 2010 The PFGRC announces the completion of the transfer of its Gateway® Entry Clone sets to the Biodefense and Emerging Infections Resources Repository (BEIR)
The PFGRC has completed the transfer of the following Gateway® Entry Clone Resources to BEIR for distribution to the scientific community: SARS coronavirus, Rickettsia prowazekii, Francisella tularensis, Helicobacter pylori, Staphylococcus aureus, 2009 H1N1 Gateway® Clones, 2009… more
October 7, 2010 The PFGRC announces the addition of an Enterotoxigenic E. coli (ETEC) Expression Clone Set to the PFGRC Gateway® Entry Clone Resource
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Pathogen Functional Genomics Resource Center (PFGRC) at JCVI is pleased to announce the addition of an Enterotoxigenic E. coli (ETEC) Expression Clone Set to the PFGRC Gateway® Entry Clone Resource.… more
July 1, 2010 The PFGRC announces the transfer of the SARS Coronavirus (SARS-CoV) Gateway® Clone set to the Biodefense and Emerging Infections Resources Repository (BEIR)
The PFGRC has transferred the SARS-CoV Gateway® Entry Clone set to BEIR for repository and distribution purposes. The set consists of 27 clones in Gateway vector pDONR 221, (Invitrogen, Inc) and is based on the Genbank accession… more
June 23, 2010 PFGRC to End Acceptance of Requests for Microarrays and Custom Cloning Services on August 1
Dear Colleagues,
The Pathogen Functional Genomics Resource Center (PFGRC) is in the process of winding down its services associated with DNA microarray and Gateway clone production and distribution.
For DNA microarrays, the last day to submit requests will be… more
June 3, 2010 Katsura - Metabolic Pathway Coverage and Expression Analysis Tool
The NIAID sponsored Pathogen Functional Genomics Resource Center (PFGRC) at the J. Craig Venter Institute has developed a software tool that overlays gene expression or comparative genomic hybridization data onto KEGG metabolic pathways. The Katsura tool utilizes data from the… more
April 12, 2010 Enrollment is open for the Pathogen Functional Genomics Resource Center's two day introductory-level training course titled, "Introduction to Microarray Data Analysis" (June 14-15, 2010)
The NIAID sponsored Pathogen Functional Genomics Resource Center at the J. Craig Venter Institute announces that it will conduct a two day course titled, "Introduction to Microarray Data Analysis." The workshop will be held on the JCVI campus on June… more
March 26, 2010 The PFGRC Announces APEX Quantitative Proteomics Tool Software version 1.1
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Pathogen Functional Genomics Resource Center (PFGRC) at JCVI is pleased to announce the release of the APEX Quantitive Proteomics Tool version 1.1. New features in the APEX Tool include options… more
January 11, 2010 The PFGRC announces two new microarrays available for distribution: Enterococcus faecalis and Escherichia coli O157:H7.
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Pathogen Functional Genomics Resource Center (PFGRC) at the J. Craig Venter Institute (JCVI) announces the addition of two new glass slide microarray resources, Enterococcus faecalis and Escherichia coli O157:H7. The… more
January 6, 2010 The PFGRC Announces an Expanded Gateway® Entry Clone Set for Streptococcus pneumoniae TIGR4
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Pathogen Functional Genomics Resource Center (PFGRC) at the JCVI is pleased to announce the addition of 56% more Gateway® entry clones to the Streptococcus pneumoniae TIGR4 Invitrogen Gateway® Entry Clone… more
August 13, 2009 The PFGRC Announces an Expanded Mycobacterium tuberculosis Gateway® Entry Clone Set
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Pathogen Functional Genomics Resource Center (PFGRC) at the JCVI is pleased to announce the addition of 30% more Gateway® entry clones to the Mycobacterium tuberculosis strains H37Rv and CDC1551 Invitrogen… more
August 3, 2009 Spaces currently available for the Pathogen Functional Genomics Resource Center's four day introductory-level training course titled,"Introduction to Microarray Technology" (September 14-17, 2009)
The NIAID sponsored Pathogen Functional Genomics Resource Center at the J. Craig Venter Institute announces that it will conduct a four day course titled, "Introduction to Microarray Technology." The workshop will be held on the JCVI campus on September 14-17,… more
July 16, 2009 M. tuberculosis knock-out clones now available through the PFGRC Gateway® Entry Clone Resource
The National Institute of Allergy and Infectious Diseases (NIAID)sponsored Pathogen Functional Genomics Resource Center (PFGRC) at JCVI,in a white paper collaboration with the Johns Hopkins School of Medicine, Department of Medicine, Division of Infectious Diseases, is pleased to announce that… more
July 1, 2009 The PFGRC Announces White Paper Collaborations for 2009
The National Institutes of Allergy and Infectious Diseases (NIAID) and the Pathogen Functional Genomics Resource Center (PFGRC) at the J Craig Venter Institute (JCVI) are pleased to announce the White Paper collaborations for 2009. The White Papers projects cover a… more
June 5, 2009 Influenza A H1N1 Outbreak Gateway® Entry Clones Now Available
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Pathogen Functional Genomics Resource Center (PFGRC) and Genome Sequencing Center of Infectious Diseases (GSCID) at JCVI are pleased to announce the availability of 29 Gateway® Entry Clones from two 2009… more
March 3, 2009 Bioinformatics Resource Center (BRC), Pathema, to host 3-day Jamboree
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Bioinformatics Resource Center (BRC), Pathema, is announcing registration of participants for a free three day Pathema Annotation Jamboree on May 13-15, 2009 on the JCVI campus. The objective of this… more
February 27, 2009 PFGRC announces the deployment of a new web ordering system for Gateway® clones
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Pathogen Functional Genomics Resource Center (PFGRC) at JCVI is pleased to announce the deployment of a new web ordering system for Gateway® clones. The new system is accessed via the… more
January 9, 2009 The Pathogen Functional Genomics Resource Center announces a program to obtain the Affymetrix E. coli FDA-ECSG microarray
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Pathogen Functional Genomics Resource Center (PFGRC) at the J. Craig Venter Institute (JCVI), in collaboration with the Center for Food Safety & Applied Nutrition of the FDA, the National Bioforensics… more
January 6, 2009 PFGRC announces the completion of the Influenza A Invitrogen Gateway® Entry Clone Resource
The National Institute of Allergy and Infectious Diseases (NIAID) sponsored Pathogen Functional Genomics Resource Center (PFGRC) and Microbial Sequencing Center (MSC) at JCVI are pleased to announce the completion of the Influenza A Invitrogen Gateway® Entry Clone Resource. The resource… more