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First Self-Replicating Synthetic Bacterial Cell

Photos

J. Craig Venter, Ph.D. and Hamilton O. Smith, M.D.

Credit: J. Craig Venter Institute

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Hamilton O. Smith, M.D. and Clyde A. Hutchison III, Ph.D.

Credit: J. Craig Venter Institute

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J. Craig Venter, Ph.D.

Credit: J. Craig Venter Institute

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Clyde A. Hutchison III, Ph.D.

Credit: J. Craig Venter Institute

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John Glass, Ph.D.

Credit: J. Craig Venter Institute

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Dan Gibson, Ph.D.

Credit: J. Craig Venter Institute

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Carole Lartigue, Ph.D.

Credit: J. Craig Venter Institute

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JCVI Synthetic Biology Team.

Credit: J. Craig Venter Institute

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Negatively stained transmission electron micrographs of aggregated M. mycoides JCVI-syn1.0. Cells using 1% uranyl acetate on pure carbon substrate visualized using JEOL 1200EX transmission electron microscope at 80 keV.

Electron micrographs were provided by Tom Deerinck and Mark Ellisman of the National Center for Microscopy and Imaging Research at the University of California at San Diego.

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Negatively stained transmission electron micrographs of dividing M. mycoides JCVI-syn1.0. Freshly fixed cells were stained using 1% uranyl acetate on pure carbon substrate visualized using JEOL 1200EX transmission electron microscope at 80 keV.

Electron micrographs were provided by Tom Deerinck and Mark Ellisman of the National Center for Microscopy and Imaging Research at the University of California at San Diego.

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Scanning electron micrographs of M. mycoides JCVI-syn1. Samples were post-fixed in osmium tetroxide, dehydrated and critical point dried with CO2 , then visualized using a Hitachi SU6600 scanning electron microscope at 2.0 keV. Electron micrographs were provided by Tom Deerinck and Mark Ellisman of the National Center for Microscopy and Imaging Research at the University of California at San Diego.

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Mycoplasma mycoides JCVI-syn1.0.

Credit: J. Craig Venter Institute

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The assembly of a synthetic M. mycoides genome in yeast.

Credit: J. Craig Venter Institute

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Images of M. mycoides JCVI-syn 1.0 and WT M. mycoides.

Credit: J. Craig Venter Institute

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Creating Bacteria from Prokaryotic Genomes Engineered in Yeast.

Credit: J. Craig Venter Institute

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Related Links

Press Release (Web | PDF)

Frequently Asked Questions (Web | PDF)

Fact Sheet: Ethical and Societal Implications/Policy Discussions about Synthetic Genomics Research (PDF)

Fact Sheet: Background/ Rationale for Creation of a Synthetic Bacterial Cell (PDF)

Funding